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Envisia® detects a genomic UIP pattern to improve ILD diagnostic and prognostic confidence

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Envisa logo showing lungs with ILD lesions
ABOUT ENVISIA®

What is the test?

Why is usual interstitial pneumonia (UIP) important for suspected interstitial lung diseases (ILD)?

UIP is a critical factor in differentiating idiopathic pulmonary fibrosis (IPF) from other ILDs to determine appropriateness of antifibrotic treatment. Additionally, UIP is associated with poor prognosis across ILD subtypes.

What is Envisia?

Envisia classifier detects the genomic pattern of UIP using transbronchial biopsy (TBB) samples to help guide diagnostic and prognostic decisions. Envisia results must be interpreted in the context of other clinical factors such as demographics, clinical history, and high resolution CT (HRCT) findings. 

Flowchart showing how Envisia test works: In patients with suspected IPF and no potential cause identified after a HRCT is performed, risk can be classified for probably UIP or indeterminate for UIP. Envisia can help reclassify into Positive for UIP, which guides IPF clinical diagnosis, or negative IPF, which guides subsequent procedures for example continuation of ILD diagnosis workup.
Play Video about Preview of "Watch brief overview of the Envisia classifier" video: a bronchoscopy procedure in the lung.

Watch brief overview of the Envisia classifier

Learn how to improve ILD diagnostic confidence with the Envisia classifier.

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Who is a good candidate for the Envisia test?

Logo of a checklist

Clinical factors:
Have no known causes
with suspected ILD

Logo depicting a high-resolution CT scan of a lung with ILD lesions

HRCT:
Probable UIP or
indeterminate for UIP

Logo depicting a lung bronchoscopy procedure in a lung with ILD lesions

Tolerability:
Able to tolerate standard
TBBx procedure

Envisia classifier results indicate either a positive or negative for UIP

Positive results

Screenshot of a patient report showing a negative Envisia test. Includes patient information and the result.
A positive result can give clinicians confidence that there is high likelihood of UIP given the high specificity of test and low likelihood of a false positive result.1
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Negative results

Screenshot of a patient report showing a positive Envisia test. Includes patient information and the result.
A negative result can provide useful information in context of clinical factors and HRCT. Continued ILD diagnosis workup may be needed.
Photo of the Envisia Sample collection kit, with a box, multiple collection tubes, and an order form.

Sample collection and ordering

Samples are collected through standard forceps transbronchial biopsy (TBB). Test results delivered within two weeks to your computer or phone. 

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References

1. Raghu G, et al. Lancet Respiratory Medicine. Apr 2019.
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How can we help?

Veracyte representatives are happy to assist you and to discuss how to integrate our tests into your practice. Monday-Friday, 5:30AM - 5PM (Pacific Time)

Client services

+1.844.464.5864 Office
+1.650.243.6335 Fax

Support email

support@veracyte.com

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